EIGHTY permanent jobs are expected to follow a large scale development at Urenco Chemplants Ltd in Capenhurst.
The company has final plans agreed for a development of almost 33,000sq m to enable the deconversion of depleted uranium hexafluoride, known as Tails, for long term safe storage.
Up to 500 construction staff could be involved by mid 2011 during the core construction period with up to 200 workers in the first phase.
The development is expected to be completed towards the end 2013.
Outline permission for the plant at the BNFL/Urenco complex was granted in 2008.
Councillors heard the facility will handle 10,350 tonnes of Tails a year.
These will be processed into 8,300 tonnes of uranium oxide. If economically viable in the future, this can be reconverted.
At a later stage, if it is thought to have no further economic value, the uranium oxide is a suitable material for disposal, according to a report.
The company says the development will provide 32,864sq m of floor space which is slightly less than the 34,545sq m agreed at the outline stage.
Overall, the majority of the buildings will be lower than previously stated.
The development will comprise a series of process areas grouped together in a large industrial building with two, much smaller, process area buildings. The uranium oxide will be packaged into containers capable of holding 10 to 12 tonnes of the product.
The facility is supported by the nuclear directorate of the Health and Safety Executive which says it will lead to a more stable and less hazardous form of uranium, more suited to long term storage, which will reduce the overall radiological hazard of the site.
Officers at Cheshire West and Chester Council said the development would be a significant reinvestment bringing regeneration benefits.