DARESBURY International Science and Technology Park is to receive a major boost in the form of £50m funding from the Northwest Regional Development Agency (NWDA).
The NWDA is to almost double its investment in the park from £25.7m to £50.3m.
The agency took the decision when it became apparent the site's potential was much greater than originally envisaged.
It was once feared the one-time nuclear accelerator research centre was doomed after a decision to site a replacement in Oxford.
But the Cheshire centre has proved a huge success, attracting world-class research and commercial operations.
A significant part of the new investment will part fund the Cock-croft Institute, the UK's National Centre for Accelerator Science, which will be located at Daresbury.
This was won by the universities of Liverpool, Lancaster and Manchester in collaboration with Accelerator Science and Technology Centre, a large team of scientists at the Council for the Central Laboratory of the Research Councils (CCLRC) Daresbury Laboratory, against strong competition.
The expansion of the science park will reaffirm Daresbury's reputation as a centre of excellence for scientific research and development and will attract significant investment to the region.
Steven Broomhead, NWDA chief executive, said: 'The NWDA is pleased to announce this substantial investment in Daresbury Science Park, reaffirming our commitment to the future of this flagship project.
'This multi-use, multi-purpose science park of international standing will attract world-class research and commercial operations that will make a significant contribution to the regional economy.'
Colin Whitehouse, director of CCLRC Daresbury Laboratory and CCLRC's chief technologist, said: 'The Cockcroft Institute will lead the way for the UK in designing and coordinating the UK contributions to the next generations of particle accelerators which are vitally important to internationally leading scientific and medical research programmes.'
