The southbound carriageway of the A41 Liverpool Road in Backford has closed today (March 23) for an estimated six days.
The road will be closed between Whitby Lane and the Moston garage traffic lights between 9am and 8pm while resurfacing work is carried out.
Motorists are advised to follow signposted diversions to A5117 Dunkirk Way and A540 Parkgate Road.
Northbound traffic flow will be maintained throughout.
A spokesman for Cheshire West and Chester Council said: "The work to resurface roughly 8,500 square metres is expected to last up to six days and the southbound carriageway will be closed between 9am and 8pm each day."