The M6 northbound is closed in Cheshire this afternoon (Thursday, May 17) following a serious collision involving four lorries.
Highways England reports all lanes blocked from junction 18 to 19, between Middlewich and Knutsford.
It tweeted: "Emergency services are working at the scene. Long delays on the approach. Please allow plenty of extra time or use an alternative route, if possible."
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The agency said the carriageway may have to be fully closed to allow the air ambulance to land.